Integrin beta 2

Quá trình sinh học

Mẫu hình biểu hiện RNA

Mẫu hình biểu hiện RNA

Thêm nguồn tham khảo về sự biểu hiện

UniProt


P05107

Bản thể genChức năng phân tửThành phần tế bàoQuá trình sinh học

Bản thể gen
Chức năng phân tử	• GO:0032403 protein-containing complex binding • metal ion binding • GO:0001948 protein binding • protein heterodimerization activity • ICAM-3 receptor activity • protein kinase binding • cell adhesion molecule binding • heat shock protein binding • amyloid-beta binding • complement component C3b binding • integrin binding • signaling receptor activity • cargo receptor activity
Thành phần tế bào	• integral component of membrane • extracellular vesicle • integrin alphaL-beta2 complex • membrane • Màng tế bào • receptor complex • cell surface • integrin complex • extracellular exosome • specific granule membrane • tertiary granule membrane • ficolin-1-rich granule membrane • focal adhesion • external side of plasma membrane • integrin alphaM-beta2 complex • plasma membrane raft • membrane raft • cytoplasmic region • protein-containing complex
Quá trình sinh học	• leukocyte cell-cell adhesion • endodermal cell differentiation • toll-like receptor 4 signaling pathway • positive regulation of nitric oxide biosynthetic process • heterotypic cell-cell adhesion • cell-cell signaling • Lão hóa • receptor internalization • leukocyte migration involved in inflammatory response • natural killer cell activation • cellular response to low-density lipoprotein particle stimulus • extracellular matrix organization • receptor clustering • positive regulation of angiogenesis • neutrophil chemotaxis • cell adhesion • positive regulation of NF-kappaB transcription factor activity • regulation of cell shape • regulation of immune response • cellular extravasation • integrin-mediated signaling pathway • cell-matrix adhesion • inflammatory response • endothelial cell migration • leukocyte migration • regulation of peptidyl-tyrosine phosphorylation • Chết rụng tế bào • Thực bào • neutrophil degranulation • microglial cell activation • receptor-mediated endocytosis • phagocytosis, engulfment • cell migration • cytokine-mediated signaling pathway • positive regulation of superoxide anion generation • cell adhesion mediated by integrin • positive regulation of neutrophil degranulation • negative regulation of dopamine metabolic process • positive regulation of protein targeting to membrane • amyloid-beta clearance • cell-cell adhesion • cell-cell adhesion via plasma-membrane adhesion molecules • positive regulation of neuron death • positive regulation of microglial cell activation • neutrophil migration • positive regulation of prostaglandin-E synthase activity • positive regulation of leukocyte adhesion to vascular endothelial cell
Nguồn: Amigo / QuickGO

Chức năng phân tử

• GO:0032403 protein-containing complex binding
• metal ion binding
• GO:0001948 protein binding
• protein heterodimerization activity
• ICAM-3 receptor activity
• protein kinase binding
• cell adhesion molecule binding
• heat shock protein binding
• amyloid-beta binding
• complement component C3b binding
• integrin binding
• signaling receptor activity
• cargo receptor activity

RefSeq (protein)


NP_000202 NP_001120963 NP_001290167

Loài

Người

Danh pháp

ITGB2, CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7, integrin subunit beta 2

RefSeq (mRNA)


NM_000211 NM_001127491 NM_001303238

ID ngoài

OMIM: 600065 HomoloGene: 20092 GeneCards: ITGB2

PubMed

[1]

PDB

Tìm trên Human UniProt: PDBe RCSB

Thành phần tế bào

• integral component of membrane
• extracellular vesicle
• integrin alphaL-beta2 complex
• membrane
• Màng tế bào
• receptor complex
• cell surface
• integrin complex
• extracellular exosome
• specific granule membrane
• tertiary granule membrane
• ficolin-1-rich granule membrane
• focal adhesion
• external side of plasma membrane
• integrin alphaM-beta2 complex
• plasma membrane raft
• membrane raft
• cytoplasmic region
• protein-containing complex

Danh sách mã id PDB

Danh sách mã id PDB
1L3Y, 1YUK, 2JF1, 2P26, 2P28, 3K6S, 3K71, 3K72, 2V7D, 4NEH, 4NEN, 5E6X, 5E6V, 5E6S, 5E6R, 5E6W, 5ES4, 5E6U

Ensembl


ENSG00000160255

Entrez


3689

Vị trí gen (UCSC)

n/a

Cấu trúc được biết đếnPDBDanh sách mã id PDB

Cấu trúc được biết đến

PDB

Tìm trên Human UniProt: PDBe RCSB

Danh sách mã id PDB
1L3Y, 1YUK, 2JF1, 2P26, 2P28, 3K6S, 3K71, 3K72, 2V7D, 4NEH, 4NEN, 5E6X, 5E6V, 5E6S, 5E6R, 5E6W, 5ES4, 5E6U